Low cost flights from Des Moines airport (DSM), USA to USA - cheap airlines
 
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Compare cheap flights from Des Moines airport (DSM), to USA Change

There are 131 flights from Des Moines airport, to USA, operated by 5 airlines. You can find a cheap flight and then book directly with the agency or airline website Des Moines airport to 89 cities in USA. List of all the cheap flights from Des Moines airport (DSM), USA
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Akron-Canton (CAK)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Akron-Canton (CAK)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Albany, NY (ALB)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Albuquerque, NM (ABQ)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Amarillo, TX (AMA)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Austin, TX (AUS)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Baltimore, MD (BWI)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Baltimore, MD (BWI)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Birmingham, AL (BHM)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Bishop (FNT)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Boise, ID (BOI)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Boston, MA (BOS)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Boston, MA (BOS)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Buffalo, NY (BUF)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Burbank, CA (BUR)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Charleston (CHS)
Notice: This could be an indirect flight
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Book low cost flight tickets with Allegiant Airways
From Des Moines (DSM)
To Charlotte County (PGD)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Charlotte, NC (CLT)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Charlotte, NC (CLT)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Chicago Midway, IL (MDW)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Chicago Midway, IL (MDW)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Cincinnati/Northern Kentucky (CVG)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Cleveland, OH (CLE)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Columbus, OH (CMH)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Corpus Christi, TX (CRP)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Dallas Love Field, TX (DAL)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Denver, CO (DEN)
Notice: This could be an indirect flight
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Book low cost flight tickets with Frontier
From Des Moines (DSM)
To Denver, CO (DEN)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Denver, CO (DEN)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Detroit Wayne County, MI (DTW)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To El Paso, TX (ELP)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Fort Lauderdale, FL (FLL)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Fort Lauderdale, FL (FLL)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To General Mitchell (MKE)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To General Mitchell (MKE)
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Book low cost flight tickets with Frontier
From Des Moines (DSM)
To General Mitchell (MKE)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Gerald R. Ford (GRR)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Greenville-Spartanburg (GSP)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Harlingen, TX (HRL)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Hartford/Springfield, CT (BDL)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Hartsfield-Jackson Atlanta (ATL)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Hartsfield-Jackson Atlanta (ATL)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Houston-Hobby, TX (HOU)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Houston-Hobby, TX (HOU)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Indianapolis, IN (IND)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Indianapolis, IN (IND)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Jacksonville, FL (JAX)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Jacksonville, FL (JAX)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To James M. Cox (DAY)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Kansas City Int'l, MO (MCI)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Las Vegas, NV (LAS)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Las Vegas, NV (LAS)
Notice: This could be an indirect flight
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Book low cost flight tickets with Allegiant Airways
From Des Moines (DSM)
To Las Vegas, NV (LAS)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Little Rock, AR (LIT)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Long Beach, CA (LGB)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Long Island/Islip, NY (ISP)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Los Angeles, CA (LAX)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Los Angeles, CA (LAX)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Louisville, KY (SDF)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Louisville, KY (SDF)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Lubbock, TX (LBB)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Manchester, NH (MHT)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Memphis (MEM)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Memphis (MEM)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Midland/Odessa, TX (MAF)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Minneapolis/St. Paul (MSP)
Notice: This could be an indirect flight
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Delta
From Des Moines (DSM)
To Minneapolis/St. Paul (MSP)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Minneapolis/St. Paul (MSP)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Nashville, TN (BNA)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To New Orleans, LA (MSY)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To New Orleans, LA (MSY)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To New York La Guardia (LGA)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To New York La Guardia (LGA)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To New York Newark (EWR)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Norfolk/Virginia Beach/Williamsburg, VA (ORF)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Oakland, CA (OAK)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Oklahoma City, OK (OKC)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Omaha, NE (OMA)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Ontario, CA (ONT)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Orlando, FL (MCO)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Orlando, FL (MCO)
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Book low cost flight tickets with Allegiant Airways
From Des Moines (DSM)
To Orlando/Sanford, FL (SFB)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Panama City Beach (ECP)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Pensacola (PNS)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Pensacola (PNS)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Philadelphia, PA (PHL)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Phoenix, AZ (PHX)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Phoenix, AZ (PHX)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Pittsburgh, PA (PIT)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Pittsburgh, PA (PIT)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Portland, ME (PWM)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Portland, ME (PWM)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Portland, OR (PDX)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Providence, RI (PVD)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Raleigh-Durham, NC (RDU)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Raleigh-Durham, NC (RDU)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Reno, NV (RNO)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Richmond, VA (RIC)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Richmond, VA (RIC)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Rochester, NY (ROC)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Rochester, NY (ROC)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Sacramento, CA (SMF)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Saint Louis, MO (STL)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Saint Louis, MO (STL)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Salt Lake City, UT (SLC)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To San Antonio, TX (SAT)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To San Antonio, TX (SAT)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To San Diego, CA (SAN)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To San Diego, CA (SAN)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To San Francisco, CA (SFO)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To San Francisco, CA (SFO)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To San Jose, CA (SJC)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Santa Ana/Orange County, CA (SNA)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Seattle, WA (SEA)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Seattle, WA (SEA)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Southwest Florida (RSW)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Southwest Florida (RSW)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Spokane, WA (GEG)
Notice: This could be an indirect flight
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Book low cost flight tickets with Allegiant Airways
From Des Moines (DSM)
To St. Petersburg-Clearwater (PIE)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Tampa/Saint Petersburg, FL (TPA)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Tampa/Saint Petersburg, FL (TPA)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Tulsa, OK (TUL)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Tuscon, AZ (TUS)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Washington (DCA)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Washington (DCA)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Washington Dulles, DC (IAD)
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Washington Dulles, DC (IAD)
Notice: This could be an indirect flight
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To West Palm Beach, FL (PBI)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To West Palm Beach, FL (PBI)
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Book low cost flight tickets with Southwest Airlines
From Des Moines (DSM)
To Wichita Mid-Continent (ICT)
Notice: This could be an indirect flight
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Book low cost flight tickets with AirTran
From Des Moines (DSM)
To Wichita Mid-Continent (ICT)
Notice: This could be an indirect flight

Tips for Flying > Buy tickets

Check the cancellation policy: Usually, if you choose the lowest fare you will not be allowed to freely modify you flight details later on (change dates or passenger names, etc). If you think that you might need to do this, you should consider buying a more flexible (but also more expensive) ticket.